Your English writing platform
Discover LudwigSuggestions(5)
Exact(9)
Computed tomography (CT) scan revealed lesions involving medulla and cortex, periosteal reaction with soft tissue component, and bone marrow infiltration in right humerus and left fibula.
Five different patterns of bone marrow infiltration in multiple myeloma have been identified on MR imaging, including a normal appearing marrow, focal infiltration, diffuse disease, salt-and-pepper involvement or combined focal and diffuse infiltration (Fig 9) [35] 35].
Open image in new window Fig. 1 Coronal T1-weighted (left) and T2-weighted STIR (right) coronal whole body MR images displaying a diffuse marrow infiltration in the spine, pelvis, femora, humeri, ribs and scapulae.
WB MRI also helps in detecting occult bone marrow infiltration in solitary plasmacytoma and allowing tumour mass assessment with hypo- or non-secretory disease.
A metaanalysis evaluating the ability of PET to identify bone marrow infiltration in (587 patients) found good (but not excellent) concordance particularly in HL and aggressive NHL [ 80].
MRI can detect bone marrow infiltration in 29 50% of patients with Durie Salmon stage I disease and negative conventional radiographs.
Similar(51)
Receiver operating characteristic (ROC) analysis showed enhancement patterns had a high level of diagnostic accuracy in assessing the degree of marrow infiltration and also in differentiating responders from non-responders.
As the bone marrow of AS is usually replaced by adipose tissue in normal adults and is expected to exhibit lower CT values (CTv) than the density of water (=0 Hounsfield Unit (HU)), bone marrow infiltration with densities in the positive range were considered to indicate myelomatous infiltration.
In the series analyzed, bone marrow infiltration was also detected in another patient, but clonality in MNC was not found.
As one would expect, the Gd-enhancement was significantly higher in marked bone marrow infiltrations than in mild or no infiltration (P<0.05) and the enhancement was higher in lesions with high vessel-density than in lesions with low vessel-density at histology (P=0.01).
Previous studies have shown that progressive bone marrow infiltration with Gaucher cells in untreated patients results in a decrease in adipocytes and thus also a decrease in fat fractions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com