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These data suggest that neutrophils may be cleared in the bone marrow in addition to the liver and spleen.
Supporting this role, in most animals our SDF-1-IRDye®800CW SDF-1-IRDye®800CW SDF-1-IRDye®800CWin addition to tumors.
Rapidly multiplying cells are more susceptible therefore it also acts on cells of GIT, bone marrow in addition to the tumor cells.
The final diagnosis of IVL with hemophagocytosis (Table 1) was made based on the presence of lymphoma cells in small vessels in the biopsy specimen of the skin, lung, or bone marrow in addition to the abnormal large lymphocytes in the bone marrow and their phenotype by flow cytometry as described above.
This is supported by data from magnetic resonance imaging (MRI) studies in patients with RA which have unraveled a high frequency of signal alterations in the juxta-articular bone marrow in addition to synovitis outside the cortical bone barrier [ 33, 34].
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Of note, mesenchymal stem cells also inhabit the bone marrow and, in addition to their role in repopulating tissues of mesenchymal origin, have a regulatory role stimulating hematopoietic stem cell growth and differentiation (reviewed in Uccelli, et al).
However, whether a more precise assessment of CR including bone marrow examination in addition to serologic testing is necessary has not yet been evaluated.
His treatment employed demineralized bone matrix and autologous bone marrow injection in addition to intramedullary nailing for the stabilization of bone cysts.
High-dose corticosteroids are commonly prescribed with induction, or to treat rejection or graft-versus-host disease, as after bone marrow transplant, in addition to being part of their long-term immunosuppression for many.
We suggest that cytopenias, the detection of which constitute pillars of the diagnostic algorithm of SLE, are the consequence of abnormal bone marrow function, in addition to specific antibody mediated direct damage.
Recent studies however have indicated that bone marrow derived cells in addition to their roles in the primary tumor also promote metastasis through their effects at secondary sites.
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