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In particular, as HIV antigenemia has been shown to affect both bone marrow function and IL-7R peripheral expression [24], [25], we reasoned that HAART-treated lymphopenic patients with full viremia suppression (immunological nonresponders, INRs) might feature a different IL-7/IL-7R profile than individuals with complete immune-virological failure (complete failure, CFs).
Finally, multiple lines of evidence suggest that central neural control, integrally regulates aspects of bone marrow function and immunological response [71], [72] and a number of studies have established that there is a central control mechanism that regulates bone remodeling [73], [74].
RDW may indicate a severe inflammatory process, with impact on bone marrow function and iron metabolism.
Patients with ECOG performance status ⩽2, adequate renal, hepatic, and bone marrow function, and radiologically measurable NPC, were eligible.
The ECOG performance status of 2 or better, adequate hepatic, renal and bone marrow function, and platelet count were required.
In patients with normal bone marrow function and iron storage, the distribution of In-Cl3 is similar to that of the 99mTc-labelled colloids (Fig. 1) [ 25].
Similar(37)
Inclusion criteria were cyto-histologically proven stage IIIB-IV NSCLC; age of 70 years or less; Eastern Cooperative Oncology Group (ECOG) perfomance status of 2 or less; normal cardiac, hepatic, renal and bone marrow functions; and no previous chemotherapy.
Inclusion criteria consisted of: ECOG performance status 0 or I, normal renal, liver, bone marrow functions and measurable disease.
has been shown in healthy sheep where slow i.v. infusion or rapid i.v. injection of honey at different concentrations (5% and 40% in normal saline or sterile distilled water) was safe, could lower blood sugar and improved renal, hepatic, and bone marrow functions and the lipid profile [ 46].
Strict dose reduction schedules based on prior toxicity and in between cycle safety laboratory measurements of bone marrow function, renal and liver function and serum creatinine phosphokinase are mandatory and are to be adhered to by the treating physician's team.
A Karnofsky performance status (KPS) ⩾70% (i.e. ECOG 0 1), adequate liver and bone marrow function parameters and bidimensionally measurable tumour lesions were mandatory.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com