Sentence examples for marrow conditions from inspiring English sources
Haemoglobinopathies such as, thalassemia and Sickle Cell Disease (SCD), and dysfunctional bone marrow conditions such as Myelodysplastic Syndromes (MDS) are all examples of diseases requiring chronic blood transfusion.
She was recently diagnosed with MDS, a rare blood and bone marrow condition, after her battle with breast cancer.
In the presence of bone marrow conditioned media (Long Term Bone Marrow Media conditioned through 7 day contact with haematopoietically active, adipocyte-rich BMS) PC-3/PC3-GFP cells adopted an amoeboid phenotype.
Additionally, electron microscopy revealed that PC-3 cells bound to junctional areas of confluent BMEC layer in the presence of bone marrow conditioned media became morphologically round, with a blebbing form consistent with an amoeboid phenotype before TEM.
This may be attributable to low levels of SDF-1 in the bones or bone marrow, a condition that would block the CXCR4/SDF-1 pathway.
Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartilage injuries.
In adult mammals the usual site of erythropoiesis is bone marrow, however, under conditions of anaemic stress (e.g. caused by acute bleeding or parasitic infection) the spleen can become a major site of red blood cell (RBC) production.
It is not known which factors exactly cause egress of blood cells from the bone marrow under normal conditions.
The detection of MPO in stromal macrophages is consistent with the hypothesis that neutrophils are being destroyed within the bone marrow under homeostatic conditions.
In contrast, in the bone marrow under homeostatic conditions, our data indicate that the phagocytosis of apoptotic neutrophils by resident macrophages stimulates their production of G-CSF.
We have previously shown that the return of senescent CXCR4high neutrophils to the bone marrow under homeostatic conditions is dependent on the SDF-1α/CXCR4 chemokine axis.
