Sentence examples for marrow compartment in from inspiring English sources
Retroviral gene therapy combined with bone marrow stem cell transplantation can be used to generate mice with ectopic gene expression in the bone marrow compartment in a quick and cost effective manner when compared to generating and maintaining transgenic mouse lines.
We could find no significant difference in numbers of HSCs or cells derived from them in the bone marrow suggesting that loss of PECAM-1 does not affect hematopoietic homeostatic mechanisms in the bone marrow compartment in the resting state.
In contrast, the marrow compartment in the metaphysis has a stem cell supply, which might already be sufficient.
In humans, hematopoiesis is defined by the formation of blood cells exclusively in the bone marrow compartment in normal conditions.
These analyses support the TMR red staining and suggest that the cells of the marrow compartment, in contrast to the outer cell layers of the bone and the epiphyses, are most viable within the first two days of culture.
There is increased F-FLT uptake in the bone marrow areas compared with that in healthy control subjects and a significant expansion of the bone marrow compartment in patients with MDS (Fig. 4b).
The model of chemotherapy is based on transient cell depletions of bone marrow compartments in dependence on drugs and drug doses.
While pre-differentiated osteoblasts in the marrow compartment only play a minor role in bone wound healing, a more prominent role is that of undifferentiated MSCs which are recruited to the regeneration site where they differentiate into osteoblasts [16].
Preliminary in vivo experiments indicate that feeding mice D3T results in an induction of QR in the bone marrow compartment such that stromal cells are more resistant to hydroquinone-induced cytotoxicity in vitro.
Using the gating strategy outlined previously [6], we found that 400-day-old Drf1−/−RhoB−/− mice had an increased percentage of granulocytes and a concomitant decrease in lymphocytes in the bone marrow compartment (Fig. 3A).
Imaging of hypoxia and programmed cell death in the bone marrow compartment are two features that may be used in the future for monitoring disease activity or for studying the effects of therapy including chemotherapy, kinase inhibitors or radiotherapy [ 71].
