Sentence examples for marrow chimeras described from inspiring English sources

(C ) CD44 MFI on CD62L+Foxp3−CD4+ splenocytes from mixed bone marrow chimeras described in Figure 7F.

Of the chimeras described, none exceeded CEL6A specific activity on phosphoric acid swollen cellulose (PASC).

To determine whether decreased Th2 cytokines and attenuated pathophysiology observed in B cell −/− mice were dependent upon antigen presentation by B cells, we used mixed bone marrow chimeras, as previously described [27].

Bone marrow chimeras were produced as described (Chen et al., 2008), using a total of 5 × 10 bone marrow cells from either WT or Neu1−/− mice as donors, and WT mice as recipients.

Because of the limited availability of PLCγ2−/− animals, some of the in vitro experiments were performed on cells from PLCγ2−/− (and appropriate control) bone marrow chimeras generated and tested as described [ 26].

Bone marrow chimeras were generated using the Ly5.1/5.2 reconstitution system, as previously described [6].

To generate adult yolk sac hematopoietic or bone marrow chimeras, embryos were transferred into phase III host shells and cultured to hatching as described [ 18].

Due to the limited availability of PI3Kβ−/− mice, bone marrow cells for most in vitro osteoclast and macrophage cultures were obtained from bone marrow chimeras generated by transplanting PI3Kβ−/− (and parallel wild-type control) mouse bone marrow cells to lethally irradiated recipients, as previously described (24, 25).

In this report we used 4-1BB-deficient mice and bone marrow chimeras to address this issue.

We observed comparable percentages of lymphocyte subpopulations in wild-type chimeras and mixed bone marrow chimeras (Figure S5A), indicating normal lymphopoiesis in mixed bone marrow chimeras.

Bone marrow chimeras were analyzed at 4 8 weeks post-bone marrow transfer (BMT).