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We studied the protective properties of bone marrow cells on the human myocardium and investigated the underlying mechanism.
Proliferation and spreading of fibroblasts and bone marrow cells on silk scaffolds were observed to be dependent on scaffold porosity as revealed through confocal microscopic observations.
The aim of this study was to examine the spontaneous in vivo recolonization potential of xenogeneic decellularized heart valves in a lamb model and the effects of granulocyte colony-stimulating factor mobilization of bone marrow cells on this process.
In this work we investigated the effects of allogeneic and syngeneic non adherent bone marrow cells on the reconstitution of hematopoiesis in lethally irradiated CD4−/− C57Bl/6 mice transgenic for human CD4 and HLA-DR3 (triple transgenic mice, TTG) [25], [26].
We seeded bone marrow cells on plastic dishes in medium containing serum, removed floating cells four days thereafter, and added PDGF-BB to the adherent cells.
We next tested the effect of PLCγ2 deficiency on osteoclast-mediated bone resorption by culturing bone marrow cells on an artificial hydroxyapatite layer.
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In this study we investigated the ability of rat bone marrow cells to proliferate and differentiate on alginates of differing composition and purity.
The Stockholm team was hoping that with the help of stem-cell-stimulating drugs, the marrow cells placed on the windpipe would start to become the right kinds of cells on both the inside and outside of the organ.
In vitro experiments support this since rat bone marrow cells cultured on human, rat, and goat PRP gels performed best on rat PRP gels by stimulating initial growth and bone differentiation [ 38].
Rat bone marrow cells cultured on scaffolds for 28 days under static conditions in osteogenic and adipogenic media respectively led to induction of differentiation.
An inverse relationship between cell number and crystal surface area was found and marrow cells grown on OCP crystals expressed osteocalcin and osteopontin mRNA, markers of osteoblastic differentiation, even in the absence of inductive media additives.
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