Sentence examples for marrow blast reduction from inspiring English sources

Partial response (PR) was defined as bone marrow blast reduction of at least 50% from baseline to 5 25% and meeting the peripheral blood criteria for CR.

Twentypercentt achieved a reduction in marrow blast count, with less than 5% blasts at morphologic exam.

In 70% of AML patients, there was a 50% reduction of peripheral blood blast cells, and in 25% of patients a 50% reduction in bone marrow blast cells.

Patients with a reduction in bone marrow blast count or stable disease and no persistent, clinically significant nonhaematological adverse event (AE) after the first induction cycle were eligible for reinduction, to be initiated no earlier than day 15 and no later than day 57.

This hypothesis is further strengthened by our observation that the pretherapeutic levels and the AUC 2 4 of nucleosomal DNA, reflecting the immediate effect of therapy, were related to the percentual reduction of bone marrow blast number from days 1 to 16.

However, pretherapeutic nucleosomal DNA levels correlated inversely with bone marrow blast number after 16 days (r = -0.55; p = 0.012) and with the relative reduction of blast number from day 1 to 16 (r = 0.58; p = 0.007).

ELN response was achieved in 21.0% of the 371 patients (CI95% 17.0 25.5) and did not depend on bone marrow blast cell percentage.

Furthermore, FLT3 expression showed a weak but significant correlation with bone marrow blast counts (r = 0.36, p = 0.049).

*Bone marrow blast percentage.

Factors negatively influencing response were AML (vs. MDS), marrow blast count, pretreatment, and transfusion dependency.

No change in bone marrow blast count was observed in two patients on day 15.