Sentence examples for marrow blast cut-point from inspiring English sources

Of note, we found that the majority of CMML patients were classified as World Health Organization CMML-1 and that a 7.5% bone marrow blast cut-point may discriminate prognosis with higher resolution in comparison with the existing 10%.

We next attempted to identify the most appropriate blast cut-point using a survival regression tree approach.

A new BM blast cut-point should therefore be validated under central pathology review and subsequently be considered as a revision to the current CMML classification schema.

The revised IPSS (IPSS-R), also developed in untreated MDS patients, refines risk group definitions by assigning greater weight to the cytogenetic risk categories, the depth of cytopenias and by altering bone marrow blast percentage cutoff points.

Our data suggest that a cut-point of 7.5% blasts may be a more appropriate discriminator of prognosis in CMML.

We were able to demonstrate that a cut-point of 7.5% BM blasts may provide improved prognostication, as cases with 5 9% blasts had a similar OS compared with those with >10% blasts.

Furthermore, patients with a bone marrow blast count up to 10% receive a score of 0.5 points in the IPSS classification (Table  1) [ 3].

By testing every possible cut-point between 3% and 15% BM blasts, this method calculated an estimated relative event rate for each group and determined that 7.5% is the optimal cut-point based on a likelihood ratio test splitting criteria.

Furthermore, FLT3 expression showed a weak but significant correlation with bone marrow blast counts (r = 0.36, p = 0.049).

*Bone marrow blast percentage.

Twentypercentt achieved a reduction in marrow blast count, with less than 5% blasts at morphologic exam.