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Using ORFK9, ORF26 and ORF72 primer sets, we screened bone marrow biopsies from 18 cases of multiple myeloma, and failed to detect any KSHV sequences.
The new lines were derived from skin cells and in one case bone marrow biopsies from patients with complex genetic diseases such as childhood diabetes, as well as rare single-gene disorders including Huntington's disease.
We extended these analyses of MM by immunohistochemical studies using a tissue microarray containing bone marrow biopsies from 20 normal controls and 20 patients with MM.
Bacterial loads in bone marrow biopsies from enteric fever patients have been shown to be significantly higher than bacterial loads in peripheral blood [ 16].
Likewise, in bone marrow biopsies from acute myeloid leukemia (AML) as well as myelodysplastic syndrome patients, blasts have been found to be positive for PD-L1, whereas stroma/non-blast cellular compartment was positive for PD-1.
To investigate whether metastatic neuroblastoma cells in bone marrow express polySia-NCAM, like their polySia-NCAM positive primary tumor foci, 19 paraffin-embedded bone marrow biopsies from six different patients were labeled with the fluorescent fusion protein.
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Bone marrow involvement was assessed by an aspiration and bone marrow biopsy from iliac crest.
Blind bone marrow biopsy from the iliac crest represents the established method to detect BMI.
Patent 1 had a PCR-positive urine sample in gestational week 10, but results of PCR on a bone marrow biopsy from gestational week 15 and PCR on amniotic fluid and placenta were negative.
Two cases of HD negative for MV by IHC, an uninvolved bone marrow biopsy from an HD patient and the NHL cases studied, were all negative in the ISH studies.
About 10% of bone marrow biopsies taken from HIV patients before the start of highly active antiretroviral therapy show active signs of hemophagocytosis [ 49].
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