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However, the conditioning regimen also significantly compromises the functioning of normal cells in the bone marrow and therefore compromises their ability to regenerate the immune system.
However, the conditioning regimen also significantly compromises the functioning of normal cells in the bone marrow, and therefore compromises their ability to regenerate the immune system.
One option, pushed by conservatives, would be to maintain the ban on embryonic stem cell research while increasing financing for experiments on adult stem cells, which are obtained from blood and bone marrow and therefore pose no ethical objections.
Because increased bone mass crowds the bone marrow, resulting in a reduced amount of marrow and therefore a reduced capacity to produce red blood cells, severe anemia results.
Among the plans being considered, according to people familiar with the debate, is one that would prohibit embryonic stem cell studies but increase support for experiments involving adult stem cells, which are extracted from blood and bone marrow and therefore pose no moral questions.
Cells derived from the mesoderm, which lies between the endoderm and the ectoderm, give rise to all other tissues of the body, including the dermis of the skin, the heart, the muscle system, the urogenital system, the bones, and the bone marrow (and therefore the blood).
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In this study, we found that the CXCL8/CXCR2 pathway modulated bone marrow angiogenesis and therefore haematopoiesis.
MRI is advantageous in evaluating bone marrow involvement and therefore plays an important role in clinical decision making for patients with myeloma.
Therefore, we used Cxcr2−/− transgenic mice to test our hypothesis that CXCR2 plays a role in the repair and regeneration of bone marrow endothelium and therefore haematopoietic recovery in vivo.
From the data presented in Fig. 1, we calculate that labeled neutrophils would represent <0.13% of the total bone marrow population, and therefore we could not accurately quantify their cellular distribution by FACs analysis.
The MK drugs, which block 5-LO pathway and block cell growth, were not toxic to the bone marrow cells and therefore may be of some use in controlling the growth of breast cancer cells opening new avenues for therapeutic intervention.
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