Sentence examples for marks we observed from inspiring English sources
There is still a strong NFR, and the marks we observed are present at roughly the same levels.
Consistent with the demonstrated allele specificity of the histone marks, we observed that in pUPD BWS cells the paternal-specific H3K9me3 and H4K20me3 were increased while the maternal-specific H3K4me2, H3K9ac and H3K27me3 were decreased (Fig. 1C).
In this regard, the change in asymmetric epigenetic marks we observed upon environmental drought conditions may represent an alternative mechanism for adaptation in plants, not only in Arabidopsis but also in species with larger and more complex genomes.
For the post-translational marks examined, we observed a range of alterations on the order of 45%% reductions to more than 200 % increases.
Finally, for the other histone marks tested we observed much lower overlap of EWS-FLI1, indicating that EWS-FLI1 primarily drives H3K27ac at selected promoters and enhancers throughout the genome.
Compared to previous studies the mean marking rates we observed were the highest documented so far for wild felids.
For virtually all histone modifications, the marking biases we observed were evident both with and without nucleosome normalization (Figure 1; Supplementary Figures S6 and S7), demonstrating that underlying nucleosome distributions could not account for the differential marking levels we observed.
In 4 5 day positively marked clones, we observed clonal sizes ranging from typically 2 11 cells (data not shown).
We believe that the marked reduction we observed in positive Monospot tests reflects a genuine decrease in the number of cases of IM.
A central finding of our study is that H3K9me3 itself cannot be the final silencing mark, as we observed strong TE derepression upon loss of Mael despite no or only very modest changes in H3K9me3.
Enhancer of Zeste homologue 2 is one of the key enzymes involved in creating the H3K27me3 mark, and we observed it to be highly expressed in the cytoplasm of CIS cells.
