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The interpretation is that the epigenetic marks under study are strongly linked to gene expression changes, but gain or loss of one single marker is usually not sufficient for transcriptional changes.
The least prevalent switches were the ones between H3K4me3 and H3K27me3, but this was coupled with the highest enrichment of dysregulated genes, suggesting that the epigenetic marks under study are strongly linked to gene expression changes, but gain or loss of one single marker is usually not sufficient for transcriptional changes.
To ensure that selected p300 peaks contain histone modification marks under study, distal p300 peaks that did not overlap any histone modification peaks were excluded.
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If no proper spot was found, then the transcript was marked as missing for the sample under study.
GLI1 and GLI2 showed marked under-expression, whereas GLI3 only tended to be under-expressed.
Table 1 shows marked differences in educational levels between the countries under study (see also [ 20]).
The binding manifests visibility of the cell under study by T-cells the hall-mark of T-cells thesystem response [ 22].
In addition, the sectors under study, dairy and meat production, are marked by certain features, which may not characterize some other agricultural sectors, and thus the member benefits may be valued very differently by other type of farmers.
Marker screening confirmed that Sr26 is absent in the panel under study (Additional file 1).
Consider the population under study.
Many risks are under study.
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CEO of Professional Science Editing for Scientists @ prosciediting.com