However, delayed gastric emptying occurs in approximately 50% of critically ill patients and, when marked, may lead to under-nutrition, gastro-oesophageal reflux and pulmonary aspiration [ 18].
Although the link between most lifestyle changes and specific epigenetic marks that may lead to disease is still unknown, MZ twins provide a good system to identify environmentally associated DNA methylation modifications and study their role in disease.
"China's huge potential, developed with its own Chinese characteristics, is now making its mark, which may lead Westerners to redefine their attitudes in accordance with the wishes of Chinese people," it says.
Mutations in this domain display marked ethno-geographic variation and may lead to failure to diagnose hepatitis B virus (HBV) infection.
One mechanism that has been proposed to explain the schedule-dependent anticancer activity of temozolomide, as well as the encouraging, although preliminary, results noted with protracted low-dose schedules, is that frequent temozolomide treatment, particularly on protracted schedules, may lead to marked, cumulative, and sustained inactivation of O-alkylguanine-DNA alkyltransferase (AGAT).
A multifaceted intervention programme targeting GPs and patients and focusing on improving diagnostic procedures in patients with RTIs may lead to a marked reduction in antibiotic prescribing.
This phenomenon, together with a simultaneous increase in venous return, may lead to a marked right ventricular enlargement during weaning, thus impeding the diastolic filling of the left ventricle through an interventricular dependence mechanism [ 10, 25].
Our results suggest that marked changes of PM air pollution may lead to cardiac autonomic imbalance in young healthy individuals, as indicated by declines in several 5-min HRV indices in taxi drivers.
Ito et al. (2007) assert that the low allocation of marks to writing in the Japanese test may lead to a lack of teachers' attention to writing activities in Japanese high schools.
Though marks are not deducted for not attempting the questions in serial order, there can be inconvenience to the paper checker and sometimes it may lead to loss of marks accidentally.
