Sentence examples for marks in normal from inspiring English sources

For example, a Leica® DM EP microscope did not show all the growth marks in normal light visible with the Leica® DM 2500.

These maps show epigenetic marks in normal umbilical vein endothelial cells HUVEC, leukemic cell line K562 and normal epidermal keratinocytes Nhek.

Obtaining a better understanding of the mechanisms of maintaining the proper balance and distribution of methyl marks in normal tissues will be critical for understanding how disruption of this balance contributes to cancer.

To identify the genomic regions differing in their chromatin state between normal and tumor tissues (Methods), the results were split in fifteen so called transitions each representing a combined state of one or more marks in normal and tumor.

In addition, three genes common to both patients which carried bivalent marks in normal and lost H3K4me3 in tumor, LHX9, PKNOX2 and LBXCOR1 and one, PRDM8, lost the H3K27me3 in tumor, all of which are transcription factors with unknown function in colon.

The start codon and stop codon of SiLEA14 are marked in normal red case.

In order to test whether genes with the H3K27me3 mark in normal colon overlapped more with genes hypermethylated in CRC than genes that carried the histone mark in tumor samples, the lists of H3K27me3 genes was compared with those previously reported as frequently hypermethylated in CRC [ 48].

Among genes with a silent state (H3K27me3 mark) in normal colon that became active in CRC samples (gained H3K4me3) there were several well-characterized oncogenes [ 32- 36], e.g. in patient 1 FLI1, WWTR1 & ZEB2 and in patient 2 TACSTD2 & TWIST1), the last two with proposed importance in CRC [ 32, 35].

Genes that undergo silencing by de novo methylation in cancer are the same subset of genes that are marked with the repressive chromatin mark HsK27me3 in normal colonic cells.

injection of this tumour induced marked thrombocytopenia in normal mice.

For the H3K27me3 unique groups, the hypersilencing pattern was still found for those genes carrying that histone mark only in normal colon samples.