Exact(5)
"So far, the marks appear to be good".
These other marks appear to depend on SET-25 activity, as H3K9me2 was not detected in set-25 ; met-2 double mutants (Towbin et al. 2012).
Our data reinforce the idea that GATA4 may be a dosage-sensitive major player in heart development, as different genetic and genomic mutations as well as primary or secondary epigenetic marks appear to contribute to the risk of CHD.
Going forward, it will be important to tease apart if or how the Set1-like MLL1/MLL2 complexes, of which MEN1 is a component, specifically generate the sharp peak of H3K4 trimethylated histones versus the broader peak of dimethylated histones at the 5' end of genes, since these two methyl marks appear to foster the opposing activities of acetylation and deacetylation.
In vivo alcohol intake or in vitro lipopolysaccharide treatment (an inflammatory stimulus) can induce H3K9/S10 phosphorylation at the promoter of cytokine genes [ 97, 98] and these specific histone marks appear to be required for NF-κB recruitment to the gene promoter [ 99].
Similar(55)
The use of specific domains to "read" the methylation marks appears to have been present in the ancestral eukaryote itself.
The bonus system, by providing the incentive to gain extra marks, appears to have motivated students to work harder and consistently.
Even though the performance is not as accurate as using all 15 acetylations, including more marks appears to contribute incrementally to the curves, such as using the top six marks (<2% change in TP for FP > 1%).
Increased repressive marks in the susceptible line correlated with significant downregulation of the genes, while in line 63, the increase in both marks appeared to compensate for each other with no eventual effect on gene transcription.
At the early pachytene stage, γH2AX had almost disappeared from the chromatin of the autosomes, but there were still some visible traces of marks on autosomes, and marks appeared to cover the sex chromosomes.
It is well established that methylation of GSTpi is a marker of prostate cancer, and global patterns of histone marking appear to be linked to cancer prognosis with levels of acetylated histones H3K9, H3K18, and H4K12, and of dimethylated H4R3 and H3K4, dividing low-grade prostate cancer (Gleason 6 or less) into two prognostically separate groups.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com