Sentence examples for marks and expression from inspiring English sources
We surmise that the ability of Myc to broadly affect the epigenetic marks and expression of genes important in pluripotency and differentiation is related for Myc's role as a reprogramming factor critical in the generation of iPS cells.
The expression values used for the correlation between marks and expression were averaged expression values from all replicates in each dataset.
Recent investigations have also suggested that 5-aza has broader effects than purely as a demethylating agent, including altering activating histone modifications to repressive marks, and expression changes independent of promoter methylation (Komashko et al, 2008).
And it even had its own much imitated style, consisting of freely used quotation marks and expressions such as "down the dumper", "yoiks!" and "sniiiiip!" Heat magazine nowadays has some of the same feel, but – Gordon Bennett! – it's no Smash Hits.
Therefore the histone mark and expression correlations may not hold for the germline.
After differentiating the sequencing reads derived from B73 and Mo17 genomes, we determined the allele-specifically expressed genes by combining allele-specific epigenetic marks and RNA expression.
The gene expression programs regulated by the Myc transcription factor were evaluated by integrated genome-wide profiling of Myc binding sites, chromatin marks and RNA expression in several biological models.
Here we integrate fine-resolution architecture maps with epigenetic marks and gene expression in embryonic stem cells (ESCs), neural progenitor cells (NPCs), and NPC-derived induced pluripotent stem cells (iPSCs).
Analysis of our data with respect to protein-coding genes reveals expected relationships between epigenetic marks and gene expression levels.
All four clusters were highly enriched in H3K27me3 marks and maintained expression silencing in ES cells [13].
Reassuringly, several studies have confirmed that TFs binding indeed correlates with the presence of "active" marks and with expression.
