Sentence examples for marking correlates from inspiring English sources

Consistent with this idea, repressive H3K27me3 marking correlates best with transcription at loci that display 'blanketing'-type H3K27me3 enrichment, that is, gene body-wide (downstream of the transcription start site (TSS)) [ 26].

We found that adenoviral marking correlated closely with CAR expression with a linear correlation coefficient (r 2 ) of 0.891 and P-value of 0.00054, thereby supporting a linear relationship of these events.

To determine whether CAR expression and adenoviral marking correlate with cell cycle, we performed a gated analysis of adenoviral marking and CAR expression.

In melanoma cells, Lian et al. [ 85] showed by genome-wide analysis a considerable reduction in 5-hmC marking, correlating with disease progression.

If H3K9me2 marks correlate with reduced transcription of nearby/adjacent genes, then we might expect to see a significant increase in transcript levels in the met-2 (0) mutant where those marks are absent, and this pattern might be especially obvious in the him-8 background where H3K9me2 marks are elevated.

The loss of the H3K27 repressive mark correlates with the higher transcription of Arf and Ink4a in senescent and Polycomb mutant cells (Fig. 1A).

The presence of this mark correlates with increased exclusion of the final 83 base pairs of CDH1 exon 8 in the mature CDH1 mRNA.

SiRNA-mediated knockdown of SETD2 (The specific methyltransferase of H3K36) decreased exclusion of exon 8, suggesting that the presence of this mark correlates with increased skipping of the final 83 base pairs of CDH1 exon 8.

The chromosomal region encompassing the CDH1 exon 8 is highly enriched in H3K36me3 marks in GC cells compared to human gastric mucosal epithelial cells, and the presence of this mark correlates with increased skipping of the final 83 base pairs of CDH1 exon 8 in the mature CDH1 mRNA.

Secondly, the ENCODE analyses are built on deep layers of previous functional genomics work, and are in essence a series of correlations: the following epigenetic marks correlate with such and such other features of the genome.

All 4 collective marks correlated with each other significantly (P < 0.001).