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Testing for both markers would identify 64/174 patients (sensitivity 37%).
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The measure provoked concern outside Iran after a Canadian newspaper, National Post, quoting "Iranian expatriates living in Canada," reported yesterday that it included provisions that would require Jews, Christians and other non-Muslims to wear colored cloth markers that would identify them.
The sequence of each of the MYB110 genes in this study was examined and PCR primer pairs were designed to create microsatellite markers that would identify each gene.
Recent efforts are focused in developing molecular markers which would identify a subset of patients in whom the benefit of the cytotoxic chemotherapy is minimal and can be omitted.
Our overall hypothesis was that a genomic marker(s) would identify responders to DrotAA and that a diagnostic kit could then be developed to help clinicians decide whom to treat with DrotAA.
Therefore, once the high-density map is constructed, these markers would help identify conserved genomic regions (i.e. synteny blocks) between the two species.
To test the effect of ATN-224 on EPCs, different cell surface markers were first evaluated for the proper identification of EPCs using bonnet macaques as a model that would identify markers that could be translated into humans.
It was expected that the study would identify important genes and functional markers for wheat yield improvement.
Moreover, the ideal diagnostic marker would preferentially identify clinically significant prostate cancers with a high risk of progression.
Also surrogate markers would help to identify patients at increased risk of cardiotoxicity.
As stated in the 2006 I-PWG publication, this approach 'takes into account that participants may change their minds during the course of the study' while also acknowledging the possibility that genetic markers would have been identified during this time that have attained clinical relevance.
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