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A fraction of the CD163+ macrophages in the implants expressed adipogenic markers, with higher levels of this "adipocyte-like" phenotype in proximity to the developing adipose tissues.
In this context, it would be worth to corroborate this result with faster genetic markers with higher resolution, extending the microsatellite analysis to the whole Mediterranean basin in order to understand if the population impacted from the MME are connected and could be naturally recovered from the P. nobilis populations located in the Tyrrhenian and Sardinian Seas.
Using native recombinant autoantigen arrays to screen autoantibody markers, it is possible to identify markers with higher sensitivity and specificity than CA-125 that are relevant to early detection of ovarian cancer.
Altogether, these results imply that the proposed method can find better diagnostic markers with higher reproducibility.
While considerable progress has been made in identifying predictive criteria for disease progression [17], [18], identification of definitive diagnostic markers with higher sensitivity and specificity are required.
Answers to these questions would require genetic markers with higher resolution as well as a spatially explicit experimental design to study colonization and succession dynamics.
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HTS-based methods can simultaneously identify multiple genetic markers with high sensitivity and specificity without individual optimization.
Extensive efforts have been devoted to developing some ultrasensitive electrochemical biosensors for detection of cancer markers with high selectivity.
At the same time, population-genetic studies have suggested that genetically diverse markers with high individual identifiability also confer information about genetic ancestry [3 6].
However, due to the low quantity of parasites present in biological samples, DNA markers with high copy number like kinetoplast minicircles are needed.
SSR markers with high cross-species transferability and high genetic diversity were selected for phylogeny analysis, where the results showed a complex genetic architecture among different sections as well as wide genetic differentiation within section Dendrobium.
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