Importantly, the on-demand release of PTHrP 107 111 had a pro-osteogenic effect, as shown by the enhancement of alkaline phosphatase activity, an early osteogenic marker, which correlated with increased expression of the osteogenic genes osteopontin and osteocalcin.
However, there has been no established clinical marker, which correlates with the response to the treatment and the prognosis in patients with NSCLC (Clinical practice guidelines for the treatment of unresectable nonsmall cell lung cancer, 1997).
Hence surrogate markers of severity of illness, which correlate with outcomes and have been validated in previous health services research in COPD, were utilized.
However, samples from both regions presented marker ions from S. terebenthifolius resins in their fingerprints, but only those from the southeast presented marker ions from Araucaria resins; which correlate well with vegetation in both locations.
In the degranulation assay, the cytotoxicity of NK cells was determined by measuring the cell surface expression of the lysosomal marker, CD107a, which correlates with NK cell cytotoxicity [ 19].
Immunological correlates of protection are biological markers such as disease-specific antibodies which correlate with protection against disease and which are measurable with immunological assays.
This algorithm is as surrogate marker of IR, more feasible for large population studies, which correlate with the euglycemic CLAMP, the gold standard for assessing IR [ 31].
So, could allow us to identify IL-27p28 SNPs as novel genetic markers which may correlate with therapy response and, possibly, with liver disease progression in HCV infected patients.
In this animal model, hyper-procalcitoninemia was an early systemic marker of sepsis which correlated closely with mortality and had an inverse correlation with serum calcium levels.
