However, these markers were weaker in overweight subjects [ 28].
In conclusion, denosumab has a strong inhibitory effect on bone resorption markers, although its inhibitory effects on bone formation markers are weak.
Thus, the two SNPs (MARC0099960, ALGA0104951) delineate a haplotype block and since LD to flanking markers is weak we conservatively use these flanking markers as coordinates and delineate our QTL to SSC12: 42,422,021–43,436,573.
However, LD with the best available SNP markers was weaker than has been reported for deletion polymorphisms in less complex regions of the genome.
While warning signs are an important aspect for early detection of potential serious disease, the evidence for any specific clinical or laboratory marker is weak.
While immunostaining for these stem cell regulators was observed in non-diseased vasculature, the IHC score for these tissues was relatively low given that staining intensity for each stem cell marker was weak to moderate and often occurred in a very small fraction (<25 %) of the cells comprising the tissue (Fig. 6, Additional file 2: Table S1).
A total of 7772 of these were produced by BACs that were not in contigs (singletons); 5946 of the markers on contigs were "weak anchors" produced by a single BAC-probe pair for the contig.
Correlations between the two oxidative stress markers at each visit were weak but statistically significant (r = 0.10 0.20, p < 0.05).
The finding that the associations between HBP and markers suggestive of increased permeability were weak could reflect the complex pathophysiology of sepsis with multiple redundant pathways leading to increased permeability [1].
In contrast, the effects of lcyE markers were found to be weak and inconsistent in the present study, which was in line with previous results [ 11, 35].The germplasm within the tropical maize gene pool is known to be more diverse than that in the temperate maize gene pool.
