The use of different endpoints, positron emission tomography for evaluation, and predictive genetic markers are recommended.
Since EMS mutagenesis is known to induce multiple mutations in the genome (Abe et al. 2012), testing with a large number of microsatellite markers is recommended before proceeding with mapping and or other applications (Wu et al. 2005; Lima et al. 2015).
Up to now no screening markers are recommended or routinely used for early detection of ovarian cancer.
Thus prudent selection of the markers based on specific population groups including usage of additional markers is recommended for efficient carrier detection.
This can be true as well for antiaging applications where, in particular, the evaluation of mTOR-related pathways and gene-expression markers is recommended as a means for the choice of geroprotectors [ 77, 94].
These biomarkers predict response to these molecular targeting agents and testing for these markers is recommended in lung cancer patients [ 12, 13], enabling personalized medicine for patients harboring EGFR mutations or ALK gene rearrangements.
However, although determination of this marker is recommended in the context of clinical trials involving alkylating agents, it cannot be recommended in routine clinical practice (Stupp and Hegi, 2007).
No specific type of incorrectly designed LAPs, common to all participants, could be defined, except for the fact that, for LAPs defined by the absence of expression of markers such as HLA-DR, inclusion of an exclusion marker is recommended.
Moreover, the SNAP markers together with our previous developed markers which were recommended as applicable marker set for evaluation of rice eating quality, will facilitate as marker-assisted selection for rice breeding program.
Although we have not used the standard markers that were recommended for MSI analysis on the basis of a National Cancer Institute Workshop (Boland et al, 1998), the results of hMLH1 and hMSH2 protein expression provide support for the validity of our study of MSI in epithelial and stromal cells.
