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To study ovarian follicular dynamics during chemotherapy to understand the mechanisms behind chemotherapy-induced ovarian follicular depletion and to evaluate whether pretreatment levels of ovarian reserve markers were predictive of the posttreatment levels.
None of the nine markers were predictive of invasive recurrence.
None of the tumour markers were predictive of outcome among grade 3 tumours.
Most of these univariately selected markers were predictive of both indications across sampling variation, supporting a correlation between disease aggressiveness and lethal outcome.
Prospective studies, 58, 157, 158 although not all, 159 showed that high bone-resorption markers were predictive of increased risk for fractures (including hip) in postmenopausal women.
However, retrospective clinicopathologic study found that none of these molecular markers were predictive of response to single-agent taxane chemotherapy in patients with metastatic breast cancer [ 36].
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We also aim to determine whether these inflammatory markers are predictive for developing some clinical implications, such as cardiovascular disease (CVD) and insulin resistance (IR), associated with PCOS.
However, to answer this important question, the MPE-model is an appropriate, clinically relevant prototype to determine if cells that are segregated on the basis of candidate CSC markers are predictive of a distinct tumorigenic or invasive phenotype.
Both markers are predictive for increased risk of VTE.
None of the markers was predictive of invasive recurrence.
Furthermore, the combined assessment of all three molecular markers was predictive for tumour progression.
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