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In HNF1α-inhibited cells, hepatocyte and epithelial markers were diminished and mesenchymal markers were over-expressed.
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By contrast, anteriorly the floor plate was specified and, although expression of floor plate markers was diminished, the dorsal expansion of ventral markers (Olig2 and Nkx6.1) and contraction of a dorsal marker (Pax7) would suggest that the anterior neural tube is ventralized.
Pofut1/Tgfb3-Cre hair follicles displayed aberrant telogen morphology at the first telogen and their bulge stem cell markers (CD34, K15, and Sox9) were diminished with a concomitant increase of K14-positive keratinocytes populating in the isthmus.
Despite rapid epithelial regeneration after DA treatment, expression of the normal phenotypic markers, Clara cell secretory protein and acetylated tubulin, were diminished.
Oxidative stress markers such as lipid peroxidation and protein carbonyl groups were increased, while the hepatic levels of reduced glutathione and antioxidant enzymes were diminished [ 40].
Abdominal sounds were diminished.
Similarly, expression of adipocyte marker, aP2, was diminished from day 15 onwards (Fig. 3E).
As expected, PGC marker expression was diminished in response to increasing levels of Mix (Fig. 6A).
In addition, accumulation in lysosomes of the fluid phase marker, dextran, is diminished.
In contrast, expression of the aboral ectoderm differentiation marker CyIIIa is diminished to an equivalent extent by knockdown of either SpRunt-1 or SpCBFβ, as are expression of two other putative SpRunt-1 targets [ 7], SpCyclinD and SpDri (the latter encodes a transcription factor required both for oral ectoderm differentiation and skeletogenesis [ 23]) (Fig. 6A).
For achieving DR in an arbitrary scene, vision-based tracking methods are considered more feasible than artificial markers that should be diminished in the user's perspective too.
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CEO of Professional Science Editing for Scientists @ prosciediting.com