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These markers were constrained to match their order on the physical map during linkage map construction in joinmap[ 35]; the likelihood of the constrained versus unconstrained marker orders was tested in R/qtl [ 36], showing only nominally less strong support for the constrained marker order (markers indicated in Additional file 1).
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Finally, the original set of 33 potential urine markers was constrained to 23 compounds detectable with the IMS instrument.
Our inferences of m j + and m j − for the two nucleic markers are constrained such that budding precedes the appearance of nuclei at the bud neck (bud+< nucneck+) and nuclei only divide after appearing at the bud neck (nucneck+< nucdiv+).
It is generally accepted that phylogeographic histories recovered using only mtDNA as a marker are constrained to reveal one genealogy that reflects the maternally inherited natural history of an organism.
Parametric methods provide stable confidence intervals but, up to now, were constrained to very special cases and required homogeneity in marker distributions in diseased and non-diseased subjects.
Customers were constrained.
Wages councils were constrained.
"Before, the police were constrained by targets.
(February sales were constrained by poor weather).
Covalent bonds were constrained using LINCS algorithm.
Water molecules were constrained using SETTLE [103].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com