Marker values before chemotherapy and at the 2-month staging of all three markers were considered significant predictors for objective treatment response.
Mean distance was calculated using the unique loci, where co-segregating markers were considered as one bin marker.
Hence, these markers were considered as tightly linked markers and used for introgressing BPH31 in the background of Jaya.
Notably, in this overview we do not provide technical details on specific risk alleles for each gene; only replicated and validated pharmacogenetic markers were considered.
The micro-deleted region was defined when 3 or more adjacent SNP markers were considered frequent LOH loci.
Mitochondrial and nuclear markers were considered congruent when all individuals from one cox1 GMYC species formed a unique PEPCK clade.
Cells positive for DAPI and negative for the tested neuronal markers were considered as non-neuronal phenotypes.
Therefore, these markers were considered appropriate to assess the cacao genepool present at the municipalities of Waslala/Rancho Grande, Nicaragua.
Proteins with ratios between the lowest and highest values for the markers were considered to be candidate mitosomal proteins.
The following markers were considered for visualization of the main types of specific brain cells: GFAP for activated astroglia, Griffonia simplifolia lectin (GSA) for activated microglia and NeuN for mature neurons.
In contrast, a subset of the DCt values obtained in the nine ICCA patients of series S1 clustered into discrete groups when the two markers were considered together (Figure 3B; Figure S2).
