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A total of 77 (or 80.2%) markers were categorized as good markers (Table S7).
For continuous variables, markers were categorized into a low and high group using the median value as the break point.
Candidate SNP markers were categorized as testcross in pair-wise comparisons of genotypes, whether a heterozygous imputation was present for one parent only (testcross) and a homozygous site was predicted for the other.
When the markers were categorized by the tertile distributions of the control group, the highest tertile of FT4 (OR = 1.73, 95% CI = 1.11 - 2.69) showed an increased risk of thyroid cancer, while the middle tertile of TSH (OR = 1.77, 95% CI = 1.14 - 2.74) was associated with thyroid cancer risk.
When the markers were categorized by the tertile distributions of the control group, the highest tertile of FT4 (OR = 1.73, 95% CI = 1.11 - 2.69) and the middle tertile of TSH (OR = 1.77, 95% CI = 1.14 - 2.74) were associated with an increased risk of thyroid cancer by multivariate analyses.
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Within Table 2, each of the 3 analysed markers was categorized as a dichotomous variable and a correlation between selected baseline patient characteristics and molecular marker results was performed.
Tissue expression of markers was categorized dichotomously as either 'over-expression' or 'under-expression', according to the 'quick score' method [ 17, 18], which multiplies the percentage of stained cells (P) by the intensity of staining (I).
If several studies on a marker are categorized as initial studies, we use the sign of the most extreme result.
Methylation of each marker was categorized into quartiles for the Kaplan-Meier curves, with quartile 1 containing the lowest values and quartile 4 containing the highest (Additional file 1: Table S3).
In total, 27 rice EST-derived markers and two grass anchor probe-derived markers, which were categorized into the five segregation types, were used for the genetic map construction of LG 3. AFLP, SSR, and SSCP data were analyzed by JoinMap 4 [ 18].
First, segregated marker loci were categorized into two parental-specific data sets by comparison of the sizes of polymorphic bands of parents and progenies.
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