Sentence examples for markers we genotyped from inspiring English sources
Using the Illumina HumanHap550 BeadChip with over 550,000 SNP markers, we genotyped 46 individuals in a three-generation Old Order Amish pedigree with 19 affected (16 BPD and three major depression) and 27 unaffected subjects.
Using nine microsatellite markers, we genotyped 1274 T.
To complement the mtDNA typing results with information from nuclear markers, we genotyped all 689 individuals at 14 microsatellite loci.
However, an MDS analysis based on the ancestry informative markers we genotyped in our sample shows that our Hispanic cases and controls cocluster with the 1,000 Genomes Project MXL individuals (Fig. 1).
In addition to these markers, we genotyped three further FOXF1 SNPs that have been previously implicated in the GWAS on Barrett's esophagus 6 resulting in a total of 90 SNPs in the replication study.
With the final set of 137,339 markers, we genotyped all 20 deeply sequenced tetrad offspring for the presence of putative NCO GCs at markers that were not found to be involved in CO-associated gene conversion (Supplementary file 2B, 'Materials and methods').
Using this marker, we genotyped the insertion in Pokalli and 20 susceptible cultivars, as well as the original donors of other seven BPH resistance genes (Bph1, bph2, bph7, Bph10, Bph18, Bph21, and Bph26) clustered on the long arm of chromosome 12 and actually allelic with each other (Zhao et al., 2016).
For genotyped markers, we coded genotypes as 0, 1, or 2 in terms of the number of observed minor alleles; for imputed markers, we used the expected genotype or 'dosage'dosage
The markers we used for genotyping are located in four different haplotype blocks (block 1: rs27356, rs27356; block 2: 3088132 and rs153929; block 3: rs28006 and rs25957; block 4: ANKH-OR and D5S1991).
To determine the accuracy of the TaqMan markers, we used them to genotype 62 individuals that had been previously genotyped using GBS.
Using 10 000- and 50 000-marker SNP microarrays, we genotyped five affected Amish children and identified a shared 8.26 Mb autozygous block on chromosome 15 that was further refined with nine additional NCS patients to a 3.96 Mb autozygous block (flanked by rs2048271 and rs959181) that contained 69 genes (Fig. 1C).
