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For continuous markers, we evaluated differences in baseline characteristics by modelling the covariate of interest by a continuous term of heart rate category in a linear model.
It is, nevertheless, noteworthy that in this cohort the inflammation markers we evaluated are significantly related to clinical outcomes [ 56, 57].
In order to allow direct comparison of individual and aggregate markers, we evaluated the individual markers equivalently using repeated random subpopulations.
To potentially capture other unmeasured variants that may not be adequately captured by single markers, we evaluated the relationship between common COX2 haplotypes and prostate risk.
Within the framework of a European Community (EC) supported longitudinal multicentre study ('CJD markers') we evaluated the specificity of 14-3-3 14-3-3 14-3-3t–Jakob dinease diagnosis from the years 1998–2008.
Among the markers we evaluated in our study, only TRACP5b was increased in patients with a primary carcinoma who progressed toward bone metastases, when compared to patients who did not develop bone metastasis.
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Since PARP cleavage is an important apoptosis marker, we evaluated whether the cleavage is distinct between the two cell lines.
In addition to silencing the luciferase marker, we evaluated the ability of different carriers to deliver siRNA targeting the Raf-1 oncogene in vivo.
To assess the quality of sodium bisulfite conversion and the subsequent PCR/pyrosequencing assays, using the LINE-1 marker, we evaluated conversion of 40 FFPE DNAs extracted using a routine method.
Based on our selection of markers, we have evaluated the effects of the Src inhibitor dasatinib on the differentiation of MSC into osteoblasts.
Given that solid tissue enzymatic disaggregation is known to cleave certain membrane markers we also evaluated how this affected the results obtained.
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