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As renin-angiotensin system (RAS) activity may affect the severity of oxidative stress and inflammatory markers, we assessed the effects of enalapril (E) and/or losartan (L) on these markers in renal transplant recipients with RAS polymorphisms.
The markers we assessed reflect different stages of B-lymphocyte activation.
For Bone turn-over markers, we assessed serum osteocalcin and C-terminal cross-linking telopeptide of type I collagen (CTX).
To assess the clinical relevance of these markers, we assessed their concentrations in clinical serum, colon tissue, and feces from CD patients.
By combined analysis of population genetics and geometric morphometric markers, we assessed gene flow among three populations of the highly specialized shrimp-feeding rock-dweller Altolamprologus compressiceps, separated by geographic distance and ecological barriers.
Given the evidence that in short-term culture, LIF supplementation maintained expression of progenitor cell markers, we assessed whether LIF maintained retinal progenitor cells and prevented neurosphere generation and differentiation.
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To test the inheritance patterns of the GFP marker, we assessed its segregation in offspring of crosses composed of known genotypes.
A total of 5'000 permutations were performed for each marker, and we assessed the proportion of permutations giving a value for the summary statistic which was more extreme than the observed (corresponding to a one-tailed test).
In addition to the circulating inflammatory and endothelial cell activation markers, we also assessed flow-mediated vasodilation as a functional test of endothelial function.
Since we previously demonstrated that morphological markers of glial 'activation' do not accurately predict the functional markers of 'activation', we assessed the levels of Ym1 messenger RNA as a marker for M2 protective microglia in the lumbar spinal cords of mSOD1 mice compared with age-matched wild-type mice (Beers et al., 2008).
With the resulting linkage map of 7802 stringently filtered markers (5417 targeted), we assessed recombination rates and genomic incongruities.
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