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To reduce genotyping errors that might arise from poor quality markers, we applied several stringent marker-filtering steps.
In order to estimate the association between repeated measurements of arsenic, cadmium, lead, selenium, and kidney markers, we applied linear mixed models.
In order to visualize in a three-dimensional space the discriminative power of all the four markers, we applied a PCA to the benign and malignant samples.
Here, in search of prognostic markers, we applied the ARACNE algorithm to find TFs that were involved in the differentiation process between IGVH subtypes.
As recommended for dominant markers, we applied a model of no admixture with correlated allele frequencies [ 63] and the optimal value of K was calculated following the method by Evanno et al. [ 64].
For these 2 markers, we applied a transcript cut-off value of 0.50 ng/μL (specificity of the cut-off is more than 90%, as confirmed in 20 healthy donor samples).
Similar(53)
At each marker, we applied a polar coordinate transformation to the X and Y intensity values on combined data from founder, F1 and DO DNA samples.
As second marker, we applied mouse monoclonal α-col IV, anti-α-dystroglycan antibodies, polyclonal α-connexin 43, or α-AQP-4 antibodies.
Our current study is primarily focused on the phylogenetic performance of agt1 compared to chloroplast markers, and thus, we applied a broad taxon sampling rather than several nSCG markers with a less dense sampling.
To investigate whether the immunointensity of ARMS was an independent prognostic marker for melanoma, we applied a multivariate Cox's proportional hazards model for the assessment of the overall survival.
Second, having identified increases in the variance of each of these measures with increasing marker number, we apply a normalising transformation to make our heterozygosity data statistically comparable.
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