However, these markers were weaker in overweight subjects [ 28].
In conclusion, denosumab has a strong inhibitory effect on bone resorption markers, although its inhibitory effects on bone formation markers are weak.
Thus, the two SNPs (MARC0099960, ALGA0104951) delineate a haplotype block and since LD to flanking markers is weak we conservatively use these flanking markers as coordinates and delineate our QTL to SSC12: 42,422,021–43,436,573.
TF expression of CM was significant in multivariate analysis, but the correlations with other coagulation markers were weak and the differences between the survivor/non-survivor groups were minimal, and this needs to be studied further.
While immunostaining for these stem cell regulators was observed in non-diseased vasculature, the IHC score for these tissues was relatively low given that staining intensity for each stem cell marker was weak to moderate and often occurred in a very small fraction (<25 %) of the cells comprising the tissue (Fig. 6, Additional file 2: Table S1).
While warning signs are an important aspect for early detection of potential serious disease, the evidence for any specific clinical or laboratory marker is weak.
Immunohistochemistry staining of endothelial cell marker CD31 was weaker in the presence of LDL, indicating that LDL induced damage to the endothelium.
For PCT, cTAL and CCD markers, a high correlation (0.66markers whereas the correlation was weaker for the glomerulus markers (R2 = 0.38).
Therefore, the signal strength for the mRNA for these markers was too weak to allow for meaningful data interpretation particularly in the case of betacellulin.
However, the strongest correlation with MIF in encephalitis was found to be for CSF polymorphonuclear leucocytes and CSF lactoferrin (a matrix protein of polymorphonuclear leukocyte-specific granules [ 20]), whereas the correlation with neopterin (a marker of CNS macrophage activation [ 21]) was weaker.
