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The scanning interval between markers was set at 0.5 cM, and the window size was set at 10 cM.
f i = P affected | i copies of the disease allele The recombination fraction between the disease locus and markers was set to θ=0 by default.
Since flow sorting yields highly pure stromal and tumor cell fractions, the threshold for complete LOH in analysis of the microsatellite markers was set high [ 19].
A 10-cM window was used to exclude closely linked cofactors, and the number of control markers was set at five (the default program setting).
The metabolite concentration in individual human plasma samples was assessed and reported relative to that of metabolites in the "model" pool, in which the concentration of all markers was set at 100.
The recombination fraction between 15 random QTL and their flanking markers was set at 0.5, i.e., complete independence (Haldane 1919), to simulate linkage equilibrium between 5% of the QTL and their flanking markers.
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As they put out into a glassy sea, familiar topographical markers are set aside.
Allele calls for inconsistent markers were set to 0 in the offending nuclear families involved in the inconsistencies.
If these two markers are set aside we find that all genes expressed in odd-numbered rhombomeres are extinguished while those in even-numbered rhombomeres are unaffected by the kto mutation.
On the left side of Figure 2E, the filter conditions 1 to 6 in Table S3B (colon-, ovand-, and pancreas-specific markers) are set to "inclusion = No" and the color patterns of the tags are almost white (low fold).
A list of useful markers is set out in Supplementary Table 2.
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