Importantly, the rare tumours that formed in the AhCre Apc fl/fl mice lost the expression of p21 (Fig 1K) and p16 (Fig 1L), suggesting that loss of these arrest/senescence markers was contributing to tumour progression.
It is possible that some of the expression of the definitive endoderm markers have been contributed by extraembryonic endoderm.
Furthermore, the ameliorated vascular endothelial function and the increased vascular remodeling marker SM22α can be contributed to one of mechanisms of the synergistic reaction.
Of these 90 B-genome marker alleles, 49 were contributed by the B. juncea parent and 41 by the B. carinata parent.
However, based on results of previous studies [ 34, 35], it can be argued that both markers could be contributing to the strong association of crtRB1 with provitamin A in maize endosperm, with the 5′TE polymorphism contributing the largest effect.
Understanding the molecular basis of OSCC progression especially invasion and metastasis and identification of potential molecular markers that are contributing to these processes is required to improve the prognosis and the survival of the patients.
Among the 426 DArTs markers that were mapped, 144 (34%) were contributed by Borneo only, 228 (53%) were contributed by P. Lilin only, while 54 (13%) were contributed by both parents.
In contrast, BayesCπ performs variable selection and assumes that a fraction 1-π of markers is not contributing to the genetic variance [ 33].
Greater reproducibility may be contributing to the improved stability in predictive performance of our subnetwork markers over single gene markers.
If markers are assumed to contribute differently to the genetic variance, an alternative approach is the use of non-linear methods for prediction of marker effects (Meuwissen et al. 2001; Habier et al. 2007; VanRaden 2008).
