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Furthermore, both in SH-SY5Y and LAN-5 the extent of inhibition of RA-dependent induction of these same differentiation markers was comparable to that observed by interfering with Ret (compare Figure 1B to Figure 3A).
The time dependent expression pattern of early and late neural/neuronal differentiation markers was comparable in f-fEBs and stEBs, indicating corresponding differentiation potentials of f-fEBs and stEBs (Figure 5A).
The decrease in metabolic bone markers was comparable to the effect seen with raloxifene.
The expression of activation markers was comparable to that of stimulated moDCs (Fig. 3, middle and bottom).
Induction of these markers was comparable in control and Bat3-depleted cells up to the 24 h time point.
Of note, the level of expression of these markers was comparable to that of p16, a commonly used senescent marker.
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In all iPSC-derived skeletal muscle cells, the expression levels of mature muscle differentiation markers were comparable to those of the human myoblast cell line Hu5/E18.
The DPI and serum albumin of survivors were significantly higher than non-survivors (0.8 ± 0.2 vs 0.5 ± 0.3 g/kg/day, p = 0.001, and 3.2 ± 0.5 vs 2.9 ± 0.5 g/dl, p = 0.03, respectively) while other markers were comparable.
Results The evolution of heart rate (HR), mean arterial pressure (MAP), biological markers were comparable between the two groups over time except a significant decrease in MAP in the OLHF group compared to CHF group only at H6 (P = 0.008) and H12 (P = 0.015) and a significant decrease in C-reactive protein level in the OLHF group at H48 (P = 0.02).
In addition, inflammatory markers were comparable in both groups.
The expression levels of the analyzed markers were comparable to those observed in mouse ESCs.
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