The enhanced production of lipid and protein oxidation markers underscores the elevated oxidative stress [ 16].
The unique advantages of optical imaging combined with the recent advances of transgenic animal models and optical molecular markers underscore the potential of diffuse optical techniques in whole-body small animal imaging [ 2].
A seminal finding that monozygotic twins are epigenetically indistinguishable early in life but, with age, exhibit substantial differences in epigenetic markers underscores the important role played by the environment in shaping the epigenome (Fraga et al. 2005).
The European guidelines, 1 for example, did not consider atrial fibrillation, unlike the contemporaneous American guidelines. 2 The large 3 and expanding array of risk markers underscores the importance of this problem, particularly since many of the markers are of uncertain causal relevance and few yet provide targets for prevention of disease.
The utility of many existing studies is limited by their use of CD25 as a Treg cell marker, underscoring the need for consistent use of Foxp3 and other specific surface markers to definitively identify Treg cells.
The authors concluded that MetS is more prevalent in lupus patients, while the correlation of MetS with inflammatory markers underscores a possible common link between chronic inflammation and increased cardiovascular risk in SLE patients.
These 2 genes provide novel subplate cellular markers and underscore the importance of genes involved in regulating neurotransmitters in developing subplate neurons.
Notably, in accordance with the literature our results further demonstrated that levels of both CD45dimCD34+KDR+ and CD45dimCD133+KDR+ EPCs and even their subpopulations coexpressing the CXCR4 surface marker were inversely correlated with HbA1c, underscoring the importance of the glycemic control for EPCs response to an AMI.
Furthermore, nuclear atypia is an unspecific morphological characteristic associated with great inter- and intraobserver variation, underscoring the need for specific molecular markers for GCTs.
However, ∼10% of patients experience relapse with dismal prognosis 2, 4, underscoring the importance of identifying reliable prognostic markers to improve the treatment of these patients.
