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The researchers chose 50 gene markers to develop a T2D classifier model and used it for risk assessment and monitoring of T2D (Qin et al. 2012).
Longitudinal studies are warranted to assess the integration of retinal vascular calibre and lens density with systemic markers to develop an overall index of biological ageing in HIV infection.
It may also be possible to exploit differential positional identity markers to develop site-directed pharmacological treatments.
With the availability of molecular markers to develop well-saturated genetic maps, mapping quantitative trait loci (QTL) has become a standard procedure to study the genetic architecture of quantitative traits, because it allows the estimation of the QTL number, their genomic position, and the genetic effects of the QTL that control them.
We then used these markers to develop a method utilizing multicolor flow cytometry to exclusively sort muscle derived venular, arterial and capillary EC which are all positive for Sca-1, CD31 and CD34 while excluding hematopoietic cells which express the common leukocyte antigen CD45.
We used these markers to develop a framework map spanning much of the genome.
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Furthermore, we applied this marker to develop an EGG test for the noninvasive detection of fetal trisomy 18.
Thus, a move from assessing each gene as an independent marker to developing robust approaches that take into account the biological relationships between markers might be necessary.
There are also efforts to find genetic markers and to develop new diagnostic tests that might more precisely identify patients who are predisposed to the type of sudden cardiac arrest a defibrillator could prevent.
A preliminary step to use DArT markers is to develop a library of DNA fragments.
Therefore, these associated markers and identified genotypes with favorable alleles can be deployed after validation for molecular marker breeding to develop heat tolerant in tall fescue.
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