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In total, we defined three marker classes using the CP (outbreeding species full-sibling family) population type implemented in JoinMap 4.0 (Van Ooijen 2006): (1) markers that segregate only in the mother (lm × ll), (2) markers that segregate only in the father (nn × np), and (3) markers that segregate in both parents (hk × hk).
In other cases, mutants are lethal and balanced with markers that segregate aneuploids.
Our in silico cellular predictions system appears to identify cell selective markers that segregate fetuses based on organ maturity.
For example, we generate highly specific variant resources from experimental crosses based on markers that segregate as expected (see the section Materials and Methods).
This will facilitate the discovery of the causative CNV and improve the design of molecular markers that segregate with the trait.
Because there are many cassava breeding programs, working with varying accessions and trait(s) of interest, a broadly useful genetic map should include markers that segregate in diverse populations.
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Separate GST values were based on marker loci completely linked to the two ecological loci and to the two inversion haplotypes, and on two unlinked markers that segregated independently of all loci under selection.
Of these, 69 segregated in the female and 70 segregated in the male parent, whereas 4 were distorted SD × SD markers that segregated in both parents.
The order of those markers that segregated in more than one population was highly consistent between the six individual mapping data sets.
We chose to monitor the expression of CD62L because it is a key marker that segregates the effector and memory T cell subsets in combination with CD44, which is expressed at high levels in all effector and memory but not in naïve T cells [14], [19].
Additionally, CATIE Type 1 has 346 segregating markers that do not segregate in the Type 2 population (Fig. 6).
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