Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that characterize primate embryonic stem cells but do not characterize other early lineages.
The human ES cell lines expressed cell surface markers that characterize undifferentiated nonhuman primate ES and human EC cells, including stage-specific embryonic antigen (SSEA)–3, SSEA-4, TRA-l-60, TRA-1-81, alkalineline phosphatase (Fig. 3) (4, 5,15, 16).
Similar to Relb-proficient cells, Relb-deficient leukemic cells presented the variable levels of CD4, CD8, CD24, and CD25 cell surface markers that characterize TEL-JAK2 leukemic cells (Figure S7).
In contrast, in epidemiological investigations, where the aim is to track disease-transmission paths and/or sources, higher typing resolution might be desired, and thus markers that characterize the complete phylogeny, or alternatively only a selected subset with high resolution, should be included in the assay.
We used several markers that characterize progenitor cells and fibroblast subpopulations.
Cell-surface markers that characterize neuro-differentiation at 28 days of culture were analyzed.
We evaluated the utility of SNPtool for the discovery of novel genomic markers that characterize the hypervirulent ST-11 lineage.
Eighteen biallelic markers that characterize the most prevalent lineages in Eastern Asia were tested using a hierarchical genotyping strategy [ 27].
The expression of SSEA-3, SSEA-4, TRA-1-60 and TRA-1-81, cell surface markers that characterize undifferentiated hESC was assessed by immunocytochemistry (Mateizel et al., 2006).
Under physiological conditions, these cells are characterized as vitamin A storing cells, displaying neuronal and neuroendocrine markers but also a variety of markers that characterize stem cells (Kordes et al. 2007; Kordes et al. 2008, 2009).
