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Thus, the prognostic value of cdc2 expression and connected markers relevant for proliferation and apoptosis has to be evaluated.
We reasoned that with a set that is more focused on markers relevant for pregnancy or DS, more and also more specific biomarkers can be found.
Expression of markers relevant for these pathomechanisms were analysed in biopsies of sIBM, polymyositis (PM), dermatomyositis (DM), dystrophic and non-myopathic muscle as controls, and cultured human myotubes.
The condensate is analysed for markers relevant for asthma and airway inflammation (IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-13 and TNF-α) [ 35] as described in earlier studies.
By contrast, blood plasma is a much more accessible biofluid and can contain markers relevant for prediction, diagnosis and/or further investigation into the cause and effects of neurological disorders.
We discuss how such data can be further evaluated by mining available databases, including expression data at the transcriptional level, as well as by additional investigations on protein and mRNA markers relevant for metabolic alterations.
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No data suggest a threshold for biological markers relevant to circulatory disease (Advisory Group on Ionising Radiation 2010; Little et al. 2010).
While amyloid deposition and variations in CSF levels of tau and Aβ represent pathophysiological markers thus relevant for disease diagnosis, the reduced metabolism (FDGPET) or atrophy (MRI) demonstrate topographic markers indicating a progression of the disease.
This prospective study assessed whether established renal markers are relevant for diagnosis and establishment of prognosis in acute heart failure.
Although, the peak area is variable depending on the sample, 2-EH can be considered as a marker compound, relevant for the identification of waterborne PU systems.
Nevertheless, by using a hierarchical approach to provide a range of acceptable marker options relevant for each patient it is hoped that, after extensive validation, this algorithm can be broadly applied across a range of clinical and geographical settings.
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