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No combination of markers provided a significantly better sensitivity at 98% specificity than the best individual marker, MUC16, in distinguishing all ovarian cancers or serous ovarian cancers from controls.
A Rigorous in silico selection of these markers provided a list of SNPs with very constant frequencies across the populations tested as demonstrated by the Fst values.
Quantifying the baseline expression of osteogenic and adipogenic differentiation markers provided a snapshot of the effects of aging and HBO on the MSC differentiation potential.
These markers provided a good coverage of the respective genes and tagged all major haplotype blocks as determined by the tagging routine [ 28] implemented in HAPLOVIEW [ 29].
Interestingly, the use of genetic markers provided a major breakthrough in the study of sexual selection, allowing for tests of paternity in natural populations but also increased opportunities for studies of post-copulatory processes during both sperm and pollen competition.
In our cohort, combination of plasma MMP8 <11.0 ng/ml and D-dimer <1.0 or <2.0 µg/ml (that is individually suboptimal cutoffs for both markers) provided a NPV of 100%.
Similar(51)
Our work offered a rapid and simple method to develop microsatellites and these novel set of SSR markers provided an effective tool for population genetics study of Rehmannia.
Therefore, we determined whether accounting for both genetic and laboratory markers provided an improved means of assessing AIDS risk.
The 8207 SNP markers provided an average coverage of about 5.3 markers for each cM in the genome.
Combining antibody titers and OGTT markers provided an AUC of 0.80 (0.73–0.87), which was significantly higher than any individual marker (P < 0.001).
Tracking of these markers provides a direct measure of deformation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com