A biological score (BS) constructed from two such markers proved to be an independent prognostic factor of survival in a multivariate analysis, considering the whole cohort of patients or solely the PTCL-NOS subgroup of tumors.
Indeed, for colon tumours the combination of markers proved to be a very strong prognostic factor, whereas for rectum tumours the combination of markers had no prognostic value.
In other clinical fields, a combination of several markers proved to be more powerful than a single-molecule approach.
Only 59 SNPs presented a Major Allele Frequency above 0.95 and 50 markers proved to be monomorphic which indicates a low false positive rate during our process of SNP calling and selection.
Analysis of a single set of markers proved more efficient to obtain smaller QTL intervals.
These surface markers proved to be useful to purify SSCs in a deterministic manner by combining multiple parameters using cell sorter [5].
In a behavioural study, information processing bias markers proved to be predictors of panic symptoms including affective, behavioral, and cognitive symptom measures [19].
In addition, the combined analysis of the two markers proved to be highly significant in the detection of colorectal polyps with a sensitivity and specificity reaching 71% and 95%, respectively, for the detection of advanced precancerous colorectal lesions.
When the people were regrouped according to their genetic markers, that proved a better guide to drug response than did their ethnic group, Dr. Goldstein reported.
SCoT markers proved to be more effective than RAPD in ascertaining genetic diversity at genotype level (% polymorphism, Rp, PIC, EMR, MI, GI and I) and population level (Na, Ne, H, I, Ht and Hs).
