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Future studies should include more patients to assure a better assessment of the novel markers' performance.
A systematic review of serum and urine biomarkers in knee and hip OA provides an overview of publications on biochemical markers performance [ 32].
However, patients with HPV infection should also be enrolled in future studies to assess the influence of HPV on the markers' performance.
An additional limitation is that we have assessed the markers' performance in identifying sepsis and severe sepsis only at the time of sampling.
Besides molecular and imaging PTSD therapy stratification/prediction markers, performance of verbal memory and mixed-handedness were postulated to be suitable as putative PTSD treatment response markers [ 118, 119].
For both groups of patients in 1994 and in 1996, the results from univariate analyzes showed no statistically significant correlation between patients' characteristics (tumour markers, performance status, tumour stage, age, number of therapeutic lines per patients) and medical decisions.
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These results showed that the markers' performances were globally close to each other, with ALP having the worst result and CYFRA 21-1 and LDH the best.
To assess the marker performance, two primer pairs from each of universal SSR markers, universal ILP markers, and universal PIP markers (Supplementary Table S9) were randomly selected, then amplified in four species: S. babylonica, Populus trichocarpa, M. notabilis, and Selaginella.
Third, we chose to use unconventional measures of marker performance.
Receiver operating characteristics (ROC) curves were plotted to quantify the marker performance.
These quantitative algorithms did not improve overall marker performance (see Supplementary Table S2).
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