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Signs of central motor neuron degeneration are often difficult to detect in clinical practice, justifying the interest for objective neuroimaging markers of upper motor neuron (UMN) involvement.
Current knowledge about the molecular properties and prognostic markers of upper tract urothelial carcinoma (UTUC) is sparse and often based on bladder urothelial carcinoma (UC), which is thought to share common risk factors with UTUC.
18 Since patency of the ductus arteriosus or foramen ovale prevent LVO and RVO from indicating systemic perfusion in the newborn, volumes of flow in the superior vena cava (SVC) and descending aorta (DAo) were also assessed as markers of upper and lower body perfusion.
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Although CgA is widely used as an indicator of enteroendocrine cells, our data therefore confirm that it is not a reliable marker of upper SI K- and L-cells.
The acquisition software measured several breathing parameters including respiratory frequency, tidal volume and time of break, which is a specific marker of upper respiratory tract irritation.
We hypothesized that beta-band (15 30 Hz) intermuscular coherence could be used as an electrophysiological marker of upper motor neuron integrity in such patients.
At E17.5, Dpy19l1-positive cells expressed Cux1, a marker of upper layer neurons (layers II-IV), although Dpy19l1 expression in the upper CP was weaker at E17.5 than at E14.5 (Fig. 3C).
Cux1, a putative marker of upper cortical layer neurones in experimental models [ 39], showed pan-cortical staining, with preferential labelling of layers II and IV and non-pyramidal cell types in keeping with recent data demonstrating expression in subsets of cortical interneurones through all cortical layers [ 15].
Abnormal results of imaging studies, aspiration cytology from ascites, elevated tumour markers (⩾2-fold of upper normal limits) of two consecutive tests at 2-week intervals, or tissue proven from biopsy, if possible, were defined as recurrence.
PPIs prescribed at some point after initiating ASA therapy might be a marker of developing upper gastrointestinal symptoms during ASA therapy in patients who may be at greater background ulcer risk than individuals not starting PPI therapy during their follow-up.
Thus, in the poorly aggressive BRC cell line interactions with promonocytes seem to lower the expression of markers of tumor malignancy (upper panel).
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