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In order to visualize the morphology of these cells, we employed antibodies raised against markers of structural plasticity, namely the polysialylated form of the neural cell adhesion molecule (PSA-NCAM) and the collapsin response mediator protein-4 (CRMP-4) (Figure 1).
We investigated four different (anatomical) markers of structural disease load and their relationship with brain activity and task performance.
Figure 3 illustrates the possible advantages of markers of structural changes over markers of loss of kidney function.
Actually, CCS and P-OPG in combination could be particular interesting as markers of structural and functional vascular calcification, respectively.
Examination of markers of structural and synaptic plasticity also provides intriguing evidence that NSCs likely improve cognition by enhancing endogenous neuronal connectivity.
Neurofilaments are markers of structural damage to axons, and raised neurofilaments in patients with ICU-AW would suggest structural damage to peripheral nerves.
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The emission from the nicotinamide ring of NADH is used as a marker of structural transformations.
This indicates that the FA is a sensitive but rather unspecific marker of structural changes.
It is therefore a marker of structural and dynamic changes of the intradimer interface.
Whereas IMT is a marker of structural vessel wall properties, arterial stiffness reflects functional wall properties.
In the assessment of C1M as a marker of structural progression in RA, we have utilized radiographic changes (JSN, mTSS and erosion score) after 24 and 52 weeks.
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