Sentence examples for markers of stemness from inspiring English sources

Markers of stemness are responsible for controlling undifferentiation and immortality in hESCs, thus they could be candidate genes for making developmental decisions in early human embryos [2], [34].

We added CD44 and Bmi1 as subsidiary markers of stemness.

Surface glycoprotein CD34 is one of the markers of stemness in mouse hematopoietic progenitors.

Researchers often rely on surrogate markers of stemness such as long-term retention of DNA labels.

In addition, TGF- β1 induces functional changes in SP− cells that migrate, form colonies and express OCT4, all markers of stemness, although they did not show motility.

This is, however, not without problems (e.g. differentiated non-proliferative cells are likely to equally retain the label) and reliable and specific markers of stemness are urgently sought.

Expression of human CD133 (human prominin-1) in cancer cells has been postulated to be a marker of stemness and is considered as a putative marker of cancer stem cells (CSCs).

OCT4B1 is highly expressed in embryonic stem cells and embryonic carcinoma cells as a putative marker of stemness, and it is rapidly downregulated during differentiation [ 12].

Importantly, in the multi-layered epithelia of the corneal limbus, C/EBPδ is upstream of p63 and thought to be a marker of stemness [22].

Additional support for self-renewal in the prostate stem cell niche is indicated by Ap2 (Table 1) that promotes proliferation over differentiation and is a marker of stemness and pluripotency [38].

It needs to be exposed that the LIF gene, an important marker of stemness [ 35], was detected to the same extent in AFCs and BM-MSCs, but was not detected in HDF; this might reflect a lower stemness of HDFs.