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To investigate the clinical potential of several markers of spinal cord ischemia in cerebrospinal fluid (CSF) and serum during aneurysm repair of the descending thoracic or thoracoabdominal aorta.
Therefore, selecting appropriate markers of spinal cord identity is necessary to determine whether regional identity is maintained in vitro.
LeX positive cells express many markers of spinal cord identity, which are largely absent from LeX negative cells.
Our data indicate that several markers of spinal cord and cortical neurospheres maintained their expression at all stages and times in culture examined.
These data demonstrate that while LeX negative cells do not, themselves, express markers of spinal cord identity, the neurospheres derived from these cells, do and imply that the LeX negative NSCs are regionalized in a manner not detected using the current set of markers.
Collectively these studies have identified S100 calcium binding protein beta (S100ß), neuron specific enolase (NSE), neurofilament protein (NFL), myelin basic protein (MBP), glial fibrillary acidic protein (GFAP), the microtubule- associated tau proteins, monocyte chemotactic protein 1 (MCP-1), and interleukins 6 and 8 (IL-6 and IL-8) as potential markers of spinal cord damage [6], [11].
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Like calretinin and somatostatin, calbindin can be used as a marker of spinal dorsal horn interneurons that do not contain GABA.
Our aim was to evaluate how common joint hypermobility is in paediatric patients with OI and to find out whether it serves as a potential predictive marker of spinal pathology in the form of scoliosis or craniovertebral anomaly.
Although this link is not surprising because both CRP as an acute phase reactant and ASspiMRI-a score as an imaging marker of spinal inflammation can be considered as objective indicators of AS inflammation.
As such, findings from the present series suggest that axonal excitability studies may be developed as a marker of spinal muscular atrophy severity and potentially incorporated into future treatment approaches.
Furthermore, the strong correlation of excitability with clinical and functional measures suggests the potential for nerve excitability to be developed as a marker of spinal muscular atrophy severity, for incorporation into assessment of future treatment approaches.
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