Sentence examples for markers of safety from inspiring English sources

In summary, this work supports the inclusion of quantified anti-HIV activity and drug levels in CVL as biomarkers of PD and PK and soluble mucosal immune mediators and endogenous activity as surrogate markers of safety in early clinical studies.

Except in two trials, laboratory markers of safety (including haematological and biochemical indices) were not available.

In accordance with previous findings [ 6, 7, 10, 11] BFR training induced neither any alteration in the laboratory markers of safety nor any clinical adverse effects.

Once specific immunological patterns associated with protective vaccination outcome or markers of safety have been reliably established, immunological big data may become useful in supporting vaccine licensing and providing an important baseline for post-licensing monitoring of safety.

In particular, effector cell therapies may cause serious adverse events even at the minimum dose level, thus dosing should be carefully carried out while monitoring predictive markers of safety such as cytokines and C‐reactive protein.

Fasted blood and urine samples were collected at 8, 10, 12, 14, 16, 20, 26, 36 and 52 weeks of age and analysed for markers of vitamin A metabolism and markers of safety including haematological and biochemical variables, bone-specific alkaline phosphatase, cross-linked carboxyterminal telopeptides of type I collagen and dual-energy X-ray absorptiometry.

The secondary objectives were to evaluate caregiver perceptions of care before and after the initiative and to follow unplanned extubation rate as a marker of safety of the initiative.

These process-induced compounds, formed by close reaction pathways, play an important role as markers of food safety and quality.

9 31 As potentially life-threatening complications that may warrant emergency treatment, perforation and PPB seem appropriate markers of patient safety.

Caution is urged when interpreting such data as surrogate markers for safety or tolerability because of the potential for bias: The attribution of reason(s) for discontinuation is complex and may be due to mild but irritating side effects, serious toxicity, lack of efficacy, non-medical reasons, or a combination of causes.

The rate of adverse events (AE) is an important marker of patient safety.