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Chromatin states were also found to be good markers of functionality across all variant classes.
It is unsurprising, therefore, that we find that DNase HSs and footprints are important markers of functionality.
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Maternal and reproductive health outcomes are important markers of the functionality of health systems.
Current knowledge indicates that AM-responsive phosphate transporters are excellent markers of AM functionality [ 47].
It has since been recognised that ERα status and markers of its functionality such as progesterone receptor (PR) provide important prognostic information, are predictive of response to anti-oestrogen therapy and broadly delineate potentially different types of breast cancers (Early Breast Cancer Trialists Collaborative Groupp, 1998).
However, our limited understanding of the complexity of HDL particles, which are heterogeneous in terms of origin, size, composition, structure and biological function, has so far hampered efforts to define a suitable marker of HDL functionality, let alone translate such measures to the clinical setting.
To determine the functionality of the E2-induced reconstructed islet vasculature network, we applied in vivo staining for lectin a commonly used marker of vessel functionality [ 33] to a group of mice treated with vehicle or E2.
[H]Serotonin uptake on platelets was used as marker of the functionality of SERT.
ABCB1 is considered to be a marker of NVU functionality, whereas the tight junction protein occludin is a marker of NVU physical integrity [ 15].
The level of HLA-DR expression is an excellent marker of monocyte functionality and anergy (that is, it correlates with decreased antigen presentation capacity and proinflammatory cytokine release).
Maintenance of expressed BRCA1 protein interaction with BARD1 was quantified, as a marker of BRCA1 functionality, and the tumor expression profiles of 27 microRNAs were determined.
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